Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 30 Reviews
8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
8
We conducted a double-blinded, placebo-controlled clinical trial to explore how myo-inositol (MI) influences insulin resistance (IR) among obese individuals with non-alcoholic fatty liver disease (NAFLD). Our study involved 48 participants who were randomly assigned to receive either 4 grams of MI or a placebo daily for eight weeks.
Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.
The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.
The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
Read More
7
We aimed to explore the effects of myo-inositol (MI) supplementation on oxidative stress in obese patients suffering from non-alcoholic fatty liver disease (NAFLD). In our double-blinded, placebo-controlled study, 51 newly diagnosed patients were divided into two groups—one receiving 4 grams of MI daily and the other receiving a placebo—while following dietary recommendations for an 8-week period.
At the end of the trial, we observed that both groups experienced significant reductions in body weight and other obesity measures. Interestingly, those taking MI showed a slightly larger decrease in weight, which was statistically significant. While there was no significant difference in most antioxidant levels between the two groups, we noted that the MI group did see a greater reduction in serum nitric oxide.
Although both groups benefited in some ways—like a decrease in feelings of hunger and desire for unhealthy foods—the MI group specifically showed a more pronounced reduction in the desire to eat fatty foods. Overall, MI supplementation positively influenced weight and certain oxidative stress markers, while also providing potential advantages in managing dietary cravings. However, we did not find significant changes in many of the oxidative stress biomarkers related to liver function, emphasizing that while MI appears beneficial for some aspects, more research is needed to fully understand its effects on liver health.
At the end of the trial, we observed that both groups experienced significant reductions in body weight and other obesity measures. Interestingly, those taking MI showed a slightly larger decrease in weight, which was statistically significant. While there was no significant difference in most antioxidant levels between the two groups, we noted that the MI group did see a greater reduction in serum nitric oxide.
Although both groups benefited in some ways—like a decrease in feelings of hunger and desire for unhealthy foods—the MI group specifically showed a more pronounced reduction in the desire to eat fatty foods. Overall, MI supplementation positively influenced weight and certain oxidative stress markers, while also providing potential advantages in managing dietary cravings. However, we did not find significant changes in many of the oxidative stress biomarkers related to liver function, emphasizing that while MI appears beneficial for some aspects, more research is needed to fully understand its effects on liver health.
Read More
Most Useful Reviews
9
Essential for fatty liver
32 people found this helpful
Inositol is vital for reducing the risk of fatty liver disease. It helps improve the flow of fat and manage excess fat accumulation in the liver. The recommended intake for conditions such as fatty liver is between 500 to 2000 mg per day, making this 500mg capsule an easy option for adjustment.
Read More
9
Effective for liver function
5 people found this helpful
I highly recommend it! I take it to improve my liver function, and find it extremely effective. I consume 6 to 8 tablets multiple times a day, and I feel great and sleep well. The price is also a blessing, allowing me to keep taking it.
Read More
8
Avoided hospital treatment
4 people found this helpful
My husband's family has struggled with fatty liver for generations. I started taking sunflower lecithin and omega 3, and after just over 3 months, I've not needed treatment during my last health check! Since starting the supplements, I've ceased my prescribed medication, which is a relief. The capsules are easy to swallow, similar in size to Japanese ones.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
- All Researches
8
We conducted a double-blinded, placebo-controlled clinical trial to explore how myo-inositol (MI) influences insulin resistance (IR) among obese individuals with non-alcoholic fatty liver disease (NAFLD). Our study involved 48 participants who were randomly assigned to receive either 4 grams of MI or a placebo daily for eight weeks.
Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.
The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.
The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
Read More
7
We aimed to explore the effects of myo-inositol (MI) supplementation on oxidative stress in obese patients suffering from non-alcoholic fatty liver disease (NAFLD). In our double-blinded, placebo-controlled study, 51 newly diagnosed patients were divided into two groups—one receiving 4 grams of MI daily and the other receiving a placebo—while following dietary recommendations for an 8-week period.
At the end of the trial, we observed that both groups experienced significant reductions in body weight and other obesity measures. Interestingly, those taking MI showed a slightly larger decrease in weight, which was statistically significant. While there was no significant difference in most antioxidant levels between the two groups, we noted that the MI group did see a greater reduction in serum nitric oxide.
Although both groups benefited in some ways—like a decrease in feelings of hunger and desire for unhealthy foods—the MI group specifically showed a more pronounced reduction in the desire to eat fatty foods. Overall, MI supplementation positively influenced weight and certain oxidative stress markers, while also providing potential advantages in managing dietary cravings. However, we did not find significant changes in many of the oxidative stress biomarkers related to liver function, emphasizing that while MI appears beneficial for some aspects, more research is needed to fully understand its effects on liver health.
At the end of the trial, we observed that both groups experienced significant reductions in body weight and other obesity measures. Interestingly, those taking MI showed a slightly larger decrease in weight, which was statistically significant. While there was no significant difference in most antioxidant levels between the two groups, we noted that the MI group did see a greater reduction in serum nitric oxide.
Although both groups benefited in some ways—like a decrease in feelings of hunger and desire for unhealthy foods—the MI group specifically showed a more pronounced reduction in the desire to eat fatty foods. Overall, MI supplementation positively influenced weight and certain oxidative stress markers, while also providing potential advantages in managing dietary cravings. However, we did not find significant changes in many of the oxidative stress biomarkers related to liver function, emphasizing that while MI appears beneficial for some aspects, more research is needed to fully understand its effects on liver health.
Read More
User Reviews
USERS' SCORE
Good
Based on 30 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Essential for fatty liver
32 people found this helpful
Inositol is vital for reducing the risk of fatty liver disease. It helps improve the flow of fat and manage excess fat accumulation in the liver. The recommended intake for conditions such as fatty liver is between 500 to 2000 mg per day, making this 500mg capsule an easy option for adjustment.
Read More
9
Effective for liver function
5 people found this helpful
I highly recommend it! I take it to improve my liver function, and find it extremely effective. I consume 6 to 8 tablets multiple times a day, and I feel great and sleep well. The price is also a blessing, allowing me to keep taking it.
Read More
8
Avoided hospital treatment
4 people found this helpful
My husband's family has struggled with fatty liver for generations. I started taking sunflower lecithin and omega 3, and after just over 3 months, I've not needed treatment during my last health check! Since starting the supplements, I've ceased my prescribed medication, which is a relief. The capsules are easy to swallow, similar in size to Japanese ones.
Read More
9
Weight loss achieved
3 people found this helpful
I found this a marvellous drug. I took it alone, alongside other medications. It effectively aids carbohydrate metabolism, combats obesity and liver disease, quickens metabolic processes, and enhances reproductive function. When combined with choline inositol and L-methionine, it drastically improved my situation, alleviating heaviness in the hypochondrium and enhancing my overall well-being.
Read More
9
Regained ovulation
1 people found this helpful
This has been a long journey in pursuit of ovulation! At 25, I struggled with an erratic cycle, and after a series of doctors' visits, I resorted to inositol. I had previously taken contraceptives, which ruined my cycle. However, after starting inositol, I finally experienced a consistent cycle and ovulation every month for the first time in years!
Read More
Frequently Asked Questions
7.5
Feeling positive results
4 people found this helpful
I purchased this to assist with infertility and improve liver function. After just a few days, I'm feeling good, indicating that it's positively impacting my liver function. I look forward to evaluating my egg count next time.
7.5
Improved energy levels
9 people found this helpful
My daughter, diagnosed with fatty liver, began using this supplement and has seen a tangible increase in her energy levels over six months, along with weight loss. Although she followed a diet, it was manageable. I believe inositol played a key role, and I've recommended it to my siblings too!
7.5
Fatty liver management
7 people found this helpful
This product has been beneficial for dealing with fatty liver disease. After consuming it for a few years, I maintained a mild fatty liver condition. However, I ceased taking it, and follow-up ultrasounds showed moderate fatty liver. Continuing to use this product alongside liver-healthy foods like Silimarin has been advantageous in preventing more serious complications.
8
Avoided hospital treatment
4 people found this helpful
My husband's family has struggled with fatty liver for generations. I started taking sunflower lecithin and omega 3, and after just over 3 months, I've not needed treatment during my last health check! Since starting the supplements, I've ceased my prescribed medication, which is a relief. The capsules are easy to swallow, similar in size to Japanese ones.
6
Aids liver metabolism
2 people found this helpful
Good working inositol! I liked this inositol. Although the effects were not immediately apparent, it definitely calmed my nervous system, reduced anxiety, and improved my sleep. Taken with vitamin C, it helps prevent the loss of inositol by nerve cells. While I understand inositol is often prescribed for hormonal balance and diabetes, I noticed it also influences fat metabolism in the liver. My appetite for fatty foods increased, whereas I previously avoided fats—yet my weight remained unchanged. Overall, this inositol works well for me.
7.5
Stable mental health
11 people found this helpful
Inositol transports nutrients to nerve cells, providing a sense of mental stability. It also enhances fat metabolism and helps control fat accumulation in the liver, which I find beneficial.
9
Weight loss achieved
3 people found this helpful
I found this a marvellous drug. I took it alone, alongside other medications. It effectively aids carbohydrate metabolism, combats obesity and liver disease, quickens metabolic processes, and enhances reproductive function. When combined with choline inositol and L-methionine, it drastically improved my situation, alleviating heaviness in the hypochondrium and enhancing my overall well-being.
7.5
Hair health
1 people found this helpful
I take inositol alongside folic acid, which is vital for health, including the reproductive system as well as the liver. It's excellent for hair health, strengthening and enhancing growth. This supplement is part of numerous hair care products, reflecting its wide-ranging benefits. If you find this review helpful, do give it a thumbs up.
8
We conducted a double-blinded, placebo-controlled clinical trial to explore how myo-inositol (MI) influences insulin resistance (IR) among obese individuals with non-alcoholic fatty liver disease (NAFLD). Our study involved 48 participants who were randomly assigned to receive either 4 grams of MI or a placebo daily for eight weeks.
Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.
The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
Throughout this period, we measured various parameters such as weight, serum glucose levels, and insulin sensitivity indices before and after the intervention. Notably, we found that MI supplementation led to significant improvements in the expression levels of key genes related to the AMPK/PI3K/AKT signaling pathway, which plays a crucial role in regulating metabolism.
The results indicated noteworthy enhancements in insulin resistance for those who received MI, measured through multiple indices, reinforcing its potential benefits for liver health management. Thus, we observed that supplementing with myo-inositol not only bolstered the expression of important metabolic genes but also helped improve insulin resistance in our participants with NAFLD.
7
We aimed to explore the effects of myo-inositol (MI) supplementation on oxidative stress in obese patients suffering from non-alcoholic fatty liver disease (NAFLD). In our double-blinded, placebo-controlled study, 51 newly diagnosed patients were divided into two groups—one receiving 4 grams of MI daily and the other receiving a placebo—while following dietary recommendations for an 8-week period.
At the end of the trial, we observed that both groups experienced significant reductions in body weight and other obesity measures. Interestingly, those taking MI showed a slightly larger decrease in weight, which was statistically significant. While there was no significant difference in most antioxidant levels between the two groups, we noted that the MI group did see a greater reduction in serum nitric oxide.
Although both groups benefited in some ways—like a decrease in feelings of hunger and desire for unhealthy foods—the MI group specifically showed a more pronounced reduction in the desire to eat fatty foods. Overall, MI supplementation positively influenced weight and certain oxidative stress markers, while also providing potential advantages in managing dietary cravings. However, we did not find significant changes in many of the oxidative stress biomarkers related to liver function, emphasizing that while MI appears beneficial for some aspects, more research is needed to fully understand its effects on liver health.
At the end of the trial, we observed that both groups experienced significant reductions in body weight and other obesity measures. Interestingly, those taking MI showed a slightly larger decrease in weight, which was statistically significant. While there was no significant difference in most antioxidant levels between the two groups, we noted that the MI group did see a greater reduction in serum nitric oxide.
Although both groups benefited in some ways—like a decrease in feelings of hunger and desire for unhealthy foods—the MI group specifically showed a more pronounced reduction in the desire to eat fatty foods. Overall, MI supplementation positively influenced weight and certain oxidative stress markers, while also providing potential advantages in managing dietary cravings. However, we did not find significant changes in many of the oxidative stress biomarkers related to liver function, emphasizing that while MI appears beneficial for some aspects, more research is needed to fully understand its effects on liver health.
References
- Aghajani T, Arefhosseini S, Ebrahimi-Mameghani M, Safaralizadeh R. The effect of myo-inositol supplementation on AMPK/PI3K/AKT pathway and insulin resistance in patients with NAFLD. Food Sci Nutr. 2024;12:7177. doi:10.1002/fsn3.4267
- Rostami S, Arefhosseini S, Tutunchi H, Khoshbaten M, Ebrahimi-Mameghani M. Does myo-inositol supplementation influence oxidative stress biomarkers in patients with non-alcoholic fatty liver disease?. Food Sci Nutr. 2024;12:1279. doi:10.1002/fsn3.3842
